SCHEMBL234461

SCHEMBL234461

O=Nc1ccc(N=O)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.58
HSD17B10 Q99714 4/20 0.58
TSHR P16473 3/20 0.58
TP53 P04637 2/20 0.58
MAPK1 P28482 2/20 0.58
HIF1A Q16665 2/20 0.58
TDP1 Q9NUW8 3/20 0.52
CYP3A4 P08684 2/20 0.52
HTT P42858 1/20 0.52
KMT2A Q03164 6/20 0.37
MAPT P10636 3/20 0.37
HPGD P15428 2/20 0.37
MEN1 O00255 2/20 0.37
CYP2C19 P33261 2/20 0.37
GMNN O75496 1/20 0.37
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
ALOX15 P16050 1/20 0.37
THPO P40225 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27660168 0.92 ALDH1A1 (0.52) ALDH1A1HSD17B10TSHRTP53MAPK1
SCHEMBL10887099 0.89 ALDH1A1 (0.50) ALDH1A1HSD17B10TSHRTP53MAPK1
SCHEMBL24385153 0.89 ALDH1A1 (0.50) ALDH1A1HSD17B10TSHRTP53MAPK1
SCHEMBL27251960 0.89 ALDH1A1 (0.50) ALDH1A1HSD17B10TSHRTP53MAPK1
SCHEMBL712641 0.86
SCHEMBL11244353 0.83 ALDH1A1 (0.52) ALDH1A1HSD17B10TSHRTP53MAPK1
SCHEMBL9139528 0.83
SCHEMBL85600 0.83
SCHEMBL246339 0.83
SCHEMBL10053525 0.83 ALDH1A1 (0.46) ALDH1A1HSD17B10TSHRTP53MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2376 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070391-A Aqueous treating agent, method for producing rubber reinforcing member, and rubber product 日本板硝子株式会社 2026-05-19 CN claimed
CN-122070366-A Cyclic RNA compositions and methods 欧纳医疗公司 2026-05-19 CN claimed
WO-2026098109-A1 PREPARATION METHOD FOR SCARLESS CIRCULAR NUCLEIC ACID MOLECULE AND APPLICATION THEREOF IN TARGETED DELIVERY 中国科学院杭州医学研究所 2026-05-15 WO claimed
WO-2026098108-A1 RECOMBINANT NUCLEIC ACID MOLECULE FOR PREPARING SCAR-FREE CIRCULAR RNA BASED ON STEM-LOOP STRUCTURE AND USE THEREOF 中国科学院杭州医学研究所 2026-05-15 WO claimed
EP-4680750-A1 COMPOSITIONS COMPRISING POLYRIBONUCLEOTIDES AND USES THEREOF Flagship Pioneering Innovations VI, LLC (US) 2026-01-21 EP claimed
EP-4680276-A1 IMMUNOGENIC COMPOSITIONS AND USES THEREOF Flagship Pioneering Innovations VI, LLC (US) 2026-01-21 EP claimed
US-20250376534-A1 CIRCULAR RNA ENCODING CHIMERIC ANTIGEN RECEPTORS TARGETING BCMA ORNA THERAPEUTICS INC (US) 2025-12-11 US claimed
EP-4634390-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2025-10-22 EP claimed
EP-4626988-A1 BIO BASED NATURAL RUBBER SOLUTIONS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2025-10-08 EP claimed
US-20250304994-A1 Circular RNA Compositions and Methods ORNA THERAPEUTICS, INC. (US) 2025-10-02 US claimed
US-4387756-A CARBON BLACK, VULCANIZER, BUTADIENE-STYRENE COPOLYMER NONSKID BRIDGESTONE TIRE COMPANY LIMITED (JP) 1983-06-14 US claimed
EP-0074233-A1 Pneumatic tires comprising an improved tread BRIDGESTONE TIRE COMPANY LIMITED (JP) 1983-03-16 EP claimed
EP-0048618-A1 Rubber composition for tires BRIDGESTONE TIRE COMPANY LIMITED (JP) 1982-03-31 EP claimed
US-4308365-A IONOMER AND P-DINITROSOBENZENE FOR BONDING RUBBERS WHITTAKER CORPORATION (US) 1981-12-29 US claimed
US-4268334-A Pipe wrapping adhesive tape method THE KENDALL COMPANY (US) 1981-05-19 US claimed
US-4111880-A POLYMERIC FILM FORMER, AROMATIC NITROSO, PHOSPHORUS COMPOUND, FILLER, PIGMENT HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1978-09-05 US claimed
US-3986629-A THERMOPLASTIC CAN END SEALANT COMPOSITION THE SOUTHLAND CORPORATION (US) 1976-10-19 US claimed
US-3950280-A THERMOPLASTIC CAN END SEALANT COMPOSITION THE SOUTHLAND CORPORATION (US) 1976-04-13 US claimed
US-3935134-A ETHYLENE-VINYL ESTER COPOLYMER, CHLORINATED POLYOLEFIN OR NATURAL RUBBER, ALKYLATED POLYPHENYL BAYER AKTIENGESELLSCHAFT (DT) 1976-01-27 US claimed
US-3935135-A ETHYLENE-VINYL ESTER COPOLYMER, CHLORINATED POLYOLEFIN OR NATURAL RUBBER, A DIPHENYL SULFONE, A DINITROSOBENZENE BAYER AKTIENGESELLSCHAFT (DT) 1976-01-27 US claimed