Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28699585 | 0.80 | GABRA1 (0.51) | GABRA1GABRB2AKR1B1CYP2D6MEN1 | |
| SCHEMBL2899906 | 0.75 | GABRA1 (0.50) | GABRA1GABRB2AKR1B1CYP2D6MEN1 | |
| SCHEMBL10796118 | 0.75 | GABRA1 (0.42) | GABRA1GABRB2AKR1B1CYP2D6KDM4E | |
| SCHEMBL10805934 | 0.73 | GABRA1 (0.47) | GABRA1GABRB2AKR1B1CYP2D6MEN1 | |
| SCHEMBL4818959 | 0.72 | GABRA1 (0.46) | GABRA1GABRB2AKR1B1CYP2D6MEN1 | |
| SCHEMBL7237376 | 0.72 | GABRA1 (0.46) | GABRA1GABRB2AKR1B1CYP2D6MEN1 | |
| SCHEMBL2909585 | 0.72 | GABRA1 (0.64) | GABRA1GABRB2AKR1B1CYP2D6MEN1 | |
| SCHEMBL2362466 | 0.71 | GABRA1 (0.61) | GABRA1GABRB2AKR1B1CYP2D6MEN1 | |
| SCHEMBL29900352 | 0.71 | GABRA1 (0.61) | GABRA1GABRB2AKR1B1CYP2D6MEN1 | |
| SCHEMBL28362254 | 0.70 | LIPG (0.45) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110862516-A | Cardo structure-containing isatin aromatic hydrocarbon copolymer, and preparation method and application thereof | 大连理工大学 | 2020-03-06 | — | — | CN | claimed |
| CN-110862516-A | Cardo structure-containing isatin aromatic hydrocarbon copolymer, and preparation method and application thereof | 大连理工大学 | 2020-03-06 | — | — | CN | disclosed |