Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28366388 | 0.88 | TNF (0.45) | KIF11PHOSPHO1G6PDTLR9SLC6A9 | |
| SCHEMBL16862008 | 0.80 | KCNH2 (0.48) | KIF11MEN1POLBKMT2ASLC6A9 | |
| SCHEMBL14966623 | 0.79 | NPC1 (0.44) | KIF11PHOSPHO1MIFMEN1POLB | |
| SCHEMBL28366314 | 0.79 | LCK (0.43) | KIF11PHOSPHO1MIFG6PDTLR9 | |
| Trifluoromethanesulfonic Acid SCHEMBL27781891 | 0.78 | POLB (0.38) | PHOSPHO1MEN1POLBKMT2AMAPT | |
| SCHEMBL28057350 | 0.77 | ALDH1A1 (0.49) | PHOSPHO1MIFG6PDTLR9MEN1 | |
| SCHEMBL9920084 | 0.75 | MEN1 (0.55) | MEN1POLBKMT2AMAPTPLEC | |
| SCHEMBL31285936 | 0.75 | TRPV1 (0.51) | PHOSPHO1G6PDTLR9MAPT | |
| SCHEMBL4648405 | 0.73 | POLB (0.39) | MIFMEN1POLBKMT2AMAPT | |
| SCHEMBL2611447 | 0.73 | HDAC8 (0.40) | MEN1POLBKMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105523996-B | Amide derivatives, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2020-03-06 | — | — | CN | disclosed |