Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 18/20 | 0.79 |
| ▸ | HTR4 | Q13639 | 17/20 | 0.79 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17709613 | 0.88 | ACHE (1.00) | ACHEHTR4SIGMAR1 | |
| SCHEMBL30139057 | 0.85 | ACHE (1.00) | ACHEHTR4SIGMAR1 | |
| SCHEMBL17709631 | 0.85 | ACHE (1.00) | ACHEHTR4SIGMAR1 | |
| SCHEMBL17709636 | 0.85 | ACHE (1.00) | ACHEHTR4SIGMAR1 | |
| SCHEMBL17709621 | 0.84 | ACHE (1.00) | ACHEHTR4SIGMAR1 | |
| SCHEMBL17709615 | 0.83 | HTR4 (1.00) | ACHEHTR4SIGMAR1 | |
| SCHEMBL17709635 | 0.83 | HTR4 (1.00) | ACHEHTR4SIGMAR1 | |
| SCHEMBL17709620 | 0.81 | HTR4 (1.00) | ACHEHTR4SIGMAR1 | |
| SCHEMBL6334014 | 0.80 | ACHE (0.68) | ACHEHTR4SIGMAR1 | |
| SCHEMBL17709634 | 0.79 | HTR4 (1.00) | ACHEHTR4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105705488-B | Compounds of acetylcholinesterase inhibitors and 5-hydroxytryptamine receptor 4 agonists, process for their preparation and pharmaceutical compositions thereof | 卡昂大学 | 2020-03-24 | — | — | CN | disclosed |