Glycerin

Glycerin

SCHEMBL28366358

C=C.CC1CO1.OCC(O)CO

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.45
ALDH1A1 P00352 1/20 0.45
THRB P10828 1/20 0.32
TDP1 Q9NUW8 1/20 0.30
CHRM2 P08172 2/20 0.30
CHRM5 P08912 2/20 0.30
CHRM3 P20309 2/20 0.30
CHRM4 P08173 1/20 0.30
MAPT P10636 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL2936531 0.95 LMNA (0.50) LMNAALDH1A1THRBTDP1CHRM2
Glycerin SCHEMBL286713 0.95 LMNA (0.50) LMNAALDH1A1THRBTDP1CHRM2
Glycerin SCHEMBL27324317 0.88 LMNA (0.43) LMNAALDH1A1THRB
Glycerin SCHEMBL28230380 0.88 LMNA (0.43) LMNAALDH1A1THRB
Glycerin SCHEMBL6552754 0.88 LMNA (0.43) LMNAALDH1A1THRB
Glycerin SCHEMBL1005401 0.88 LMNA (0.43) LMNAALDH1A1THRB
Glycerin SCHEMBL28818655 0.86 ALDH1A1 (0.41) LMNAALDH1A1
Glycerin SCHEMBL11668440 0.82 TDP1 (0.42) LMNAALDH1A1TDP1
Glycerin SCHEMBL2357917 0.82 ALDH1A1 (0.38) LMNAALDH1A1
Glycerin SCHEMBL6047073 0.81 ALDH1A1 (0.35) LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107001593-B Thermosetting resin composition 三键有限公司 2020-01-17 CN disclosed