Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10035468 | 0.77 | GSK3A (0.33) | ALDH1A1 | |
| SCHEMBL3823746 | 0.74 | ALDH1A1 (0.55) | ALDH1A1TDP1POLB | |
| SCHEMBL1931322 | 0.74 | ALDH1A1 (0.56) | ALDH1A1TDP1POLBLMNA | |
| SCHEMBL110450 | 0.69 | ALDH1A1 (0.39) | ALDH1A1TDP1POLBAADAT | |
| SCHEMBL21909372 | 0.69 | POLB (0.35) | TDP1POLBCTDSP1 | |
| SCHEMBL22895257 | 0.69 | ALDH1A1 (0.39) | ALDH1A1TDP1POLBAADAT | |
| SCHEMBL44079 | 0.68 | ATM (0.52) | ALDH1A1TDP1POLB | |
| SCHEMBL18912900 | 0.68 | ATM (0.52) | ALDH1A1TDP1POLB | |
| SCHEMBL22922483 | 0.68 | ALDH1A1 (1.00) | ALDH1A1TDP1POLBLMNA | |
| SCHEMBL18386589 | 0.68 | ALDH1A1 (1.00) | ALDH1A1TDP1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113769086-A | Targeted therapeutic drug, preparation method and application thereof | 中国科学院宁波工业技术研究院慈溪生物医学工程研究所 | 2021-12-10 | — | — | CN | claimed |
| CN-113750247-A | Tumor targeting drug, preparation method and application thereof | 中国科学院宁波工业技术研究院慈溪生物医学工程研究所 | 2021-12-07 | — | — | CN | claimed |
| CN-113750257-A | Tumor targeted imaging material, preparation method and application thereof | 中国科学院宁波工业技术研究院慈溪生物医学工程研究所 | 2021-12-07 | — | — | CN | claimed |
| CN-113769086-A | Targeted therapeutic drug, preparation method and application thereof | 中国科学院宁波工业技术研究院慈溪生物医学工程研究所 | 2021-12-10 | — | — | CN | disclosed |
| CN-113750247-A | Tumor targeting drug, preparation method and application thereof | 中国科学院宁波工业技术研究院慈溪生物医学工程研究所 | 2021-12-07 | — | — | CN | disclosed |
| CN-113750257-A | Tumor targeted imaging material, preparation method and application thereof | 中国科学院宁波工业技术研究院慈溪生物医学工程研究所 | 2021-12-07 | — | — | CN | disclosed |
| CN-109535162-B | Preparation method of N-p-aminobenzoyl glutamyl folic acid | 浙江圣达生物药业股份有限公司 | 2020-03-24 | — | — | CN | disclosed |