Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29900107 | 1.00 | ALDH1A1 (1.00) | ALDH1A1TDP1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL6052 | 1.00 | ALDH1A1 (1.00) | ALDH1A1TDP1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL18049094 | 1.00 | ALDH1A1 (1.00) | ALDH1A1TDP1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL18386589 | 1.00 | ALDH1A1 (1.00) | ALDH1A1TDP1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL525258 | 1.00 | ALDH1A1 (1.00) | ALDH1A1TDP1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL30734372 | 1.00 | ALDH1A1 (1.00) | ALDH1A1TDP1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL31289550 | 0.86 | ALDH1A1 (0.75) | ALDH1A1TDP1SMN1; SMN2L3MBTL1KMT2A | |
| Toluene SCHEMBL29171791 | 0.84 | ALDH1A1 (0.70) | ALDH1A1TDP1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL28408842 | 0.80 | ALDH1A1 (0.64) | ALDH1A1TDP1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL16592563 | 0.78 | ALDH1A1 (0.64) | ALDH1A1TDP1SMN1; SMN2L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11338038-B2 | Branched multi-functional macromonomers and related polymers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-05-24 | — | — | US | disclosed |
| US-20210130525-A1 | Functional Bottlebrush Polymers | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2021-05-06 | — | — | US | disclosed |
| US-20210023224-A1 | BRANCHED MULTI-FUNCTIONAL MACROMONOMERS AND RELATED POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2021-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11338038-B2 | Branched multi-functional macromonomers and related polymers and uses thereof | MSN, CAD, NEDD8 | ALDH1A1 469/4885TDP1 2521/4885SMN1; SMN2 2082/4885 |
| US-20210023224-A1 | BRANCHED MULTI-FUNCTIONAL MACROMONOMERS AND RELATED POLYMERS AND USES THEREOF | MSN, CAD, NEDD8 | ALDH1A1 469/4885TDP1 2521/4885SMN1; SMN2 2082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.