SCHEMBL283668

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL819721	0.87	TSHR (0.55)	TSHRCYP3A4TXNRD1MCOLN3KAT2B
	SCHEMBL2825941	0.82	TSHR (0.51)	TSHRTXNRD1VCAM1SMN1; SMN2
	SCHEMBL2060749	0.82	ATM (0.56)	TSHRCYP3A4TXNRD1VCAM1MEN1
	SCHEMBL1491788	0.82	TXNRD1 (0.46)	TSHRCYP3A4TXNRD1VCAM1MEN1
	SCHEMBL15703077	0.81	TSHR (0.60)	TSHRCYP3A4MCOLN3KAT2BVCAM1
	SCHEMBL30908542	0.81	TSHR (0.60)	TSHRCYP3A4MCOLN3KAT2BVCAM1
	SCHEMBL3891593	0.80	TXNRD1 (0.43)	TSHRCYP3A4TXNRD1VCAM1MEN1
	SCHEMBL3891584	0.80	TXNRD1 (0.43)	TSHRCYP3A4TXNRD1VCAM1MEN1
	SCHEMBL14866258	0.80	TXNRD1 (0.54)	TXNRD1MCOLN3MEN1KMT2ARAB9A
	SCHEMBL2061146	0.80	MAPT (0.55)	TSHRCYP3A4TXNRD1VCAM1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.