Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | EBP | Q15125 | 1/20 | 0.34 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28367102 | 0.86 | CYP1A2 (0.40) | L3MBTL1ALDH1A1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL28367567 | 0.79 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2EBP | |
| SCHEMBL28367014 | 0.73 | SMN1; SMN2 (0.41) | KCNH2SMN1; SMN2TSHRHRH3 | |
| SCHEMBL12082369 | 0.72 | L3MBTL3 (0.59) | KDM4EL3MBTL3L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL28363516 | 0.71 | SMN1; SMN2 (0.40) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21402730 | 0.71 | SMN1; SMN2 (0.33) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28367071 | 0.71 | AKR1C3 (0.43) | KDM4EALDH1A1AKR1C3 | |
| SCHEMBL5774548 | 0.70 | ALDH1A1 (0.43) | KDM4EL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL12237815 | 0.69 | L3MBTL3 (0.79) | KDM4EL3MBTL3L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL14924459 | 0.68 | HRH3 (0.53) | L3MBTL3L3MBTL1ALDH1A1SMN1; SMN2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110878070-B | Method for preparing asymmetric urea compound | 中国科学院化学研究所 | 2021-08-31 | — | — | CN | disclosed |
| CN-110878070-A | Method for preparing asymmetric urea compound | 中国科学院化学研究所 | 2020-03-13 | — | — | CN | disclosed |