Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.49 |
| ▸ | CES1 | P23141 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.44 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23086144 | 1.00 | CES2 (0.49) | CES2CES1NPC1JAK2RAB9A | |
| SCHEMBL11784549 | 1.00 | CES2 (0.49) | CES2CES1NPC1JAK2RAB9A | |
| SCHEMBL30404353 | 1.00 | CES2 (0.49) | CES2CES1NPC1JAK2RAB9A | |
| SCHEMBL11815719 | 0.88 | ALDH1A1 (0.59) | CES2CES1NPC1JAK2RAB9A | |
| SCHEMBL9321117 | 0.86 | ALDH1A1 (0.61) | CES2CES1NPC1JAK2RAB9A | |
| SCHEMBL9222220 | 0.84 | CES2 (0.48) | CES2CES1NPC1JAK2RAB9A | |
| SCHEMBL23064792 | 0.83 | MAPT (0.41) | ALDH1A1TP53LMNASMN1; SMN2KMT2A | |
| SCHEMBL8922653 | 0.82 | ALDH1A1 (0.54) | CES2CES1NPC1RAB9AALDH1A1 | |
| SCHEMBL21288035 | 0.81 | CES2 (0.44) | CES2CES1NPC1JAK2RAB9A | |
| SCHEMBL11272120 | 0.80 | ALDH1A1 (0.49) | NPC1RAB9AALDH1A1TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110879297-A | Lipid biomarker for detecting nephrotic syndrome rat model and application thereof | 山西大学 | 2020-03-13 | — | — | CN | claimed |