Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.62 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.62 |
| ▸ | FEN1 | P39748 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20508992 | 0.90 | PTPN1 (0.74) | MEN1KMT2ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL598345 | 0.88 | MEN1 (0.69) | MEN1KMT2ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL12532290 | 0.87 | MEN1 (0.80) | MEN1KMT2ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL38656798 | 0.80 | KMT2A (1.00) | MEN1KMT2ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL5691811 | 0.80 | PTPN1 (0.72) | MEN1KMT2ANPC1MAPTHPGD | |
| SCHEMBL8343202 | 0.79 | CES2 (0.60) | MEN1KMT2ANPC1MAPTHPGD | |
| SCHEMBL6602830 | 0.78 | PTPN1 (0.65) | MEN1KMT2ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL29702370 | 0.78 | MEN1 (0.74) | MEN1KMT2ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL1548899 | 0.78 | MEN1 (0.74) | MEN1KMT2ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL10648 | 0.78 | ALDH1A1 (0.71) | MEN1KMT2ANPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107141299-B | Substituted pyrrole chromone compound and application thereof | 中山大学 | 2020-03-13 | — | — | CN | disclosed |