SCHEMBL28367354

SCHEMBL28367354

CCOOCCCCCCCCCCCCCC(C)C

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
OPRM1 P35372 1/20 0.32
RARB P10826 1/20 0.32
KDM4C Q9H3R0 2/20 0.32
KDM4A O75164 1/20 0.32
PHF8 Q9UPP1 1/20 0.32
KDM2A Q9Y2K7 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28605866 1.00 LMNA (0.40) LMNAOPRM1RARBKDM4CKDM4A
SCHEMBL14518715 0.90 LMNA (0.38) LMNAALDH1A1
SCHEMBL28068761 0.90 LMNA (0.48) LMNARARBKDM4CKDM4APHF8
SCHEMBL71621 0.90 LMNA (0.48) LMNARARBKDM4CKDM4APHF8
SCHEMBL27278429 0.86 OPRM1 (0.42) LMNAOPRM1
SCHEMBL29253592 0.86 OPRM1 (0.42) LMNAOPRM1
SCHEMBL22442052 0.86 OPRM1 (0.42) LMNAOPRM1
SCHEMBL9149362 0.86 LMNA (0.40) LMNAOPRM1RARB
SCHEMBL30589896 0.85 LMNA (0.43) LMNARARBALDH1A1
SCHEMBL9562021 0.82 MEN1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107207740-B Method for preparing functionalized particles 美国陶氏有机硅公司 2020-03-17 CN disclosed