Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626680 | 0.87 | ALPI (0.35) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL626679 | 0.87 | ALPI (0.35) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL626690 | 0.87 | ALPI (0.35) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL4199918 | 0.86 | ALPI (0.52) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL4199926 | 0.86 | ALPI (0.52) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Water SCHEMBL15012669 | 0.85 | ALPI (0.34) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Water SCHEMBL15012752 | 0.85 | ALPI (0.34) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Water SCHEMBL15012398 | 0.85 | ALPI (0.34) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL2704117 | 0.83 | FFAR1 (0.43) | POLBALDH1A1KMT2ATSHRHDAC1 | |
| SCHEMBL609514 | 0.81 | ALDH1A1 (0.43) | ALPIPKMPTGS1XIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1530568-B1 | INDOLE OR BENZIMIDAZOLE DERIVATIVES FOR MODULATING I&kB KINASE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-12-29 | — | — | EP | claimed |