Toluene

Toluene

SCHEMBL28367651

CC(Br)Br.Cc1ccccc1

nearest known ligand 0.69

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.69
TSHR P16473 3/20 0.69
LMNA P02545 1/20 0.69
ALOX12 P18054 1/20 0.69
HPGD P15428 4/20 0.42
TDP1 Q9NUW8 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
POLB P06746 1/20 0.39
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
KCNH3 Q9ULD8 2/20 0.38
ALDH1A1 P00352 3/20 0.38
MAPK1 P28482 1/20 0.38
TAAR1 Q96RJ0 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL8844853 0.84 ACHE (0.73) ACHETSHRLMNAALOX12HPGD
Toluene SCHEMBL8772848 0.83 ACHE (0.85) ACHETSHRLMNAALOX12HPGD
Toluene SCHEMBL8938900 0.83 ACHE (1.00) ACHETSHRLMNAALOX12HPGD
SCHEMBL12344964 0.83 ACHE (1.00) ACHETSHRLMNAALOX12HPGD
Toluene SCHEMBL1 0.83
Toluene SCHEMBL175861 0.83 ACHE (1.00) ACHETSHRLMNAALOX12HPGD
Toluene SCHEMBL4535818 0.83 ACHE (1.00) ACHETSHRLMNAALOX12HPGD
SCHEMBL12344943 0.83 ACHE (1.00) ACHETSHRLMNAALOX12HPGD
Toluene SCHEMBL4429042 0.83 ACHE (1.00) ACHETSHRLMNAALOX12HPGD
Toluene SCHEMBL8824270 0.83 ACHE (1.00) ACHETSHRLMNAALOX12HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108097309-B CO (carbon monoxide)2High-efficiency catalyst for synthesizing propylene carbonate with propylene oxide and preparation method thereof 中国石油化工股份有限公司 2020-03-17 CN disclosed