SCHEMBL28367654

SCHEMBL28367654

Nc1cccc(-c2cccc(C(=O)O)c2C(=O)O)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.55
HNF4A P41235 1/20 0.46
MAOA P21397 1/20 0.46
MAP4K4 O95819 1/20 0.44
UCHL5 Q9Y5K5 1/20 0.43
MEN1 O00255 3/20 0.42
ALDH1A1 P00352 3/20 0.42
KMT2A Q03164 3/20 0.42
GAA P10253 2/20 0.42
HPGD P15428 2/20 0.42
FOLH1 Q04609 1/20 0.41
MYC P01106 1/20 0.41
MAPT P10636 3/20 0.41
HSD17B10 Q99714 2/20 0.41
THRB P10828 2/20 0.41
RECQL P46063 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
KDM4E B2RXH2 2/20 0.41
CYP3A4 P08684 2/20 0.41
CASP7 P55210 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27895544 0.90 BCAT2 (0.50) MCL1HNF4AMAOAMAP4K4UCHL5
SCHEMBL7139018 0.88 HNF4A (0.53) MCL1HNF4AALDH1A1FOLH1MYC
SCHEMBL30690111 0.86 MCL1 (0.58) MCL1HNF4AMAOAMAP4K4UCHL5
SCHEMBL29155698 0.86 MCL1 (0.58) MCL1HNF4AMAOAMAP4K4UCHL5
SCHEMBL28165441 0.85 HNF4A (0.56) MCL1HNF4AMEN1ALDH1A1KMT2A
SCHEMBL17744897 0.85 MCL1 (0.57) MCL1HNF4AMAOAMAP4K4UCHL5
SCHEMBL28567708 0.84 HNF4A (0.62) HNF4AMEN1ALDH1A1KMT2AFOLH1
SCHEMBL6852742 0.83 HNF4A (0.69) MCL1HNF4AMAOAMAP4K4UCHL5
SCHEMBL9185623 0.83 MCL1 (0.58) MCL1HNF4AMAOAMAP4K4UCHL5
SCHEMBL17744798 0.83 MCL1 (0.51) MCL1HNF4AMAOAMAP4K4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107189067-B Polyimide precursor and application thereof 长兴材料工业股份有限公司 2021-01-05 CN disclosed
CN-107312173-B polyimide precursor and use thereof 长兴材料工业股份有限公司 2019-12-17 CN disclosed