Pyrrole

Pyrrole

SCHEMBL28367709

Cc1ccc(-c2ccccc2)cc1.c1cc[nH]c1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.47
NPC1 O15118 5/20 0.47
TDP1 Q9NUW8 2/20 0.47
HPGD P15428 2/20 0.47
NFKB1 P19838 2/20 0.47
NFKB2 Q00653 2/20 0.47
RELA Q04206 2/20 0.47
POLB P06746 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ALDH1A1 P00352 4/20 0.46
KDM4E B2RXH2 2/20 0.46
LMNA P02545 1/20 0.46
TSHR P16473 1/20 0.46
ALOX12 P18054 1/20 0.46
ACHE P22303 1/20 0.46
NR1H2 P55055 1/20 0.44
NR1H3 Q13133 1/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL7180595 0.85 ACHE (0.65) RAB9ANPC1TDP1HPGDPOLB
SCHEMBL22079642 0.84 ACHE (0.62) RAB9ANPC1TDP1HPGDNFKB1
SCHEMBL7412470 0.84 ACHE (0.62) RAB9ANPC1TDP1HPGDNFKB1
SCHEMBL587 0.84 ACHE (0.62) RAB9ANPC1TDP1HPGDNFKB1
Tannin Pyrogallol SCHEMBL1419994 0.84 ACHE (0.62) RAB9ANPC1TDP1HPGDNFKB1
P-Xylene SCHEMBL27859158 0.84 ACHE (0.53) RAB9ANPC1TDP1HPGDALDH1A1
Biphenyl SCHEMBL7410367 0.84 ALDH1A1 (0.60) NPC1TDP1ALDH1A1LMNATSHR
Toluene SCHEMBL27595426 0.82 ACHE (0.61) RAB9ANPC1TDP1HPGDPOLB
Toluene SCHEMBL27729481 0.82 ACHE (0.61) RAB9ANPC1TDP1HPGDPOLB
Ammonia Solution, Strong SCHEMBL23824902 0.82 ACHE (0.59) RAB9ANPC1TDP1HPGDNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115884812-A Cleaning composition 株式会社资生堂 2023-03-31 CN disclosed
CN-115461030-A Cleaning agent composition 株式会社资生堂 2022-12-09 CN disclosed
CN-115279332-A Composition containing lamellar gel, emulsified composition and external composition for skin 株式会社资生堂 2022-11-01 CN disclosed
CN-115151239-A Oil-in-water type emulsion composition 株式会社资生堂 2022-10-04 CN disclosed
CN-114846108-A Anti-pollution material 日产化学株式会社 2022-08-02 CN disclosed
CN-114466647-A Solid water-in-oil type emulsion cosmetic 株式会社资生堂 2022-05-10 CN disclosed
CN-113873996-A Personal care compositions and malodor suppression methods 株式会社资生堂 2021-12-31 CN disclosed
CN-113329794-A Skin external preparation and method for improving ultraviolet protection effect 株式会社资生堂 2021-08-31 CN disclosed
CN-113286635-A Sunscreen cosmetic 株式会社资生堂 2021-08-20 CN disclosed
CN-113164794-A Emulsified cosmetic composition 株式会社资生堂 2021-07-23 CN disclosed
CN-113143780-A Thickening composition containing lipopeptide-type compound 日产化学工业株式会社 2021-07-23 CN disclosed
CN-113015559-A Cosmetic preparation 株式会社资生堂 2021-06-22 CN disclosed
CN-112996473-A Powder dispersion composition and dispersion method thereof 株式会社资生堂 2021-06-18 CN disclosed
CN-112891245-A Stick-shaped base material containing lipid peptide type compound 日产化学工业株式会社 2021-06-04 CN disclosed
CN-112714643-A Water-in-oil type composition for external application to skin 株式会社资生堂 2021-04-27 CN disclosed
CN-112672729-A Water-in-oil type emulsion cosmetic 株式会社资生堂 2021-04-16 CN disclosed
CN-112638359-A Composition for forming coating film 日产化学株式会社 2021-04-09 CN disclosed
CN-112638355-A Cosmetic and cleaning product 株式会社资生堂 2021-04-09 CN disclosed
CN-111565703-A Composition containing powder 日产化学株式会社 2020-08-21 CN disclosed
CN-106572957-B Skin color improving agent and composition for improving skin color 昭和电工株式会社 2020-03-27 CN disclosed