Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MAT2A | P31153 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28365129 | 0.89 | CYP19A1 (0.49) | KDM4EMAPTHTTL3MBTL1FGFR1 | |
| SCHEMBL28368802 | 0.84 | CYP19A1 (0.48) | MAPTHTTL3MBTL1NOTUMCYP1A2 | |
| SCHEMBL28365593 | 0.81 | NOTUM (0.49) | MAPTHTTFGFR1NOTUMCYP1A2 | |
| SCHEMBL28369700 | 0.80 | NOTUM (0.50) | KDM4EMAPTHTTL3MBTL1POLB | |
| SCHEMBL28202823 | 0.78 | ALDH1A1 (0.50) | KDM4EHTTL3MBTL1POLBNOTUM | |
| SCHEMBL23887272 | 0.76 | CYP19A1 (0.41) | KDM4EMAPTL3MBTL1ALDH1A1HPGD | |
| SCHEMBL30337855 | 0.76 | CYP19A1 (0.41) | KDM4EMAPTL3MBTL1ALDH1A1HPGD | |
| SCHEMBL6408242 | 0.74 | KDM4E (0.65) | KDM4EMAPTHTTL3MBTL1POLB | |
| SCHEMBL9156616 | 0.74 | POLB (0.51) | KDM4EGRIK1GRIK2MAPTHTT | |
| SCHEMBL9241483 | 0.72 | KDM4E (0.51) | KDM4EGRIK1GRIK2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107619385-B | Method for synthesizing 2-trifluoromethyl indole by palladium-catalyzed aryl enamine intramolecular amine | 温州大学 | 2020-02-21 | — | — | CN | disclosed |