Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28365127 | 0.88 | NOTUM (0.52) | NOTUMFGFR1KMT2ANPC1RAB9A | |
| SCHEMBL28365207 | 0.83 | KDM4E (0.47) | NOTUMKMT2ANPC1RAB9APLA2G10 | |
| SCHEMBL28202823 | 0.82 | ALDH1A1 (0.50) | NOTUMKMT2APLA2G10ALDH1A1MAPK1 | |
| SCHEMBL28368790 | 0.81 | KDM4E (0.44) | NOTUMFGFR1ALDH1A1CYP2A6MAPK1 | |
| SCHEMBL28369700 | 0.80 | NOTUM (0.50) | NOTUMKMT2APLA2G10ALDH1A1MAPK1 | |
| SCHEMBL11723689 | 0.78 | ALDH1A1 (0.44) | NOTUMFGFR1KMT2ANPC1RAB9A | |
| SCHEMBL13425026 | 0.77 | CYP2A6 (0.37) | KMT2ANPC1RAB9APLA2G10ALDH1A1 | |
| SCHEMBL28365347 | 0.76 | NOTUM (0.40) | NOTUMKMT2APLA2G10ALDH1A1TDP1 | |
| SCHEMBL28261128 | 0.74 | APP (0.50) | FGFR1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL28885169 | 0.73 | NOTUM (0.47) | NOTUMKMT2APLA2G10ALDH1A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107619385-B | Method for synthesizing 2-trifluoromethyl indole by palladium-catalyzed aryl enamine intramolecular amine | 温州大学 | 2020-02-21 | — | — | CN | disclosed |