Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PHGDH | O43175 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28373066 | 0.87 | PHGDH (0.44) | HTTUSP2ALDH1A1NPSR1PHGDH | |
| SCHEMBL28373065 | 0.86 | SOS1 (0.59) | ALDH1A1MAPTHPGDPKML3MBTL1 | |
| SCHEMBL28369104 | 0.85 | PHGDH (0.42) | HTTALDH1A1PHGDHMAPTHPGD | |
| SCHEMBL19281568 | 0.76 | GAA (0.54) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| Hydrochloric Acid SCHEMBL11635578 | 0.71 | L3MBTL1 (0.69) | HTTUSP2ALDH1A1NPSR1KDM4E | |
| SCHEMBL2056342 | 0.70 | ALDH1A1 (0.62) | HTTUSP2ALDH1A1NPSR1KDM4E | |
| SCHEMBL21292670 | 0.70 | PHGDH (0.80) | HTTALDH1A1NPSR1PHGDHKDM4E | |
| SCHEMBL11504470 | 0.70 | ALDH1A1 (0.56) | HTTUSP2ALDH1A1NPSR1KDM4E | |
| SCHEMBL27864603 | 0.69 | KDM4E (0.57) | HTTUSP2ALDH1A1NPSR1KDM4E | |
| SCHEMBL27896876 | 0.69 | ALDH1A1 (0.58) | HTTUSP2ALDH1A1NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106562951-B | Furan D-3-phosphoglycerate dehydrogenase allosteric inhibitor and its application | 北京大学 | 2020-02-11 | — | — | CN | disclosed |