Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30083682 | 1.00 | METAP2 (0.54) | METAP2LMNAALDH1A1MAPTCYP2C9 | |
| SCHEMBL28929936 | 0.90 | METAP2 (0.57) | METAP2LMNAALDH1A1MAPTCYP2C9 | |
| SCHEMBL28929925 | 0.90 | LMNA (0.52) | METAP2LMNAALDH1A1MAPTCYP2C9 | |
| SCHEMBL30100599 | 0.90 | LMNA (0.52) | METAP2LMNAALDH1A1MAPTCYP2C9 | |
| SCHEMBL30083699 | 0.85 | SLC16A3 (0.58) | METAP2LMNAALDH1A1MAPTCYP2C9 | |
| SCHEMBL28370447 | 0.85 | SLC16A3 (0.58) | METAP2LMNAALDH1A1MAPTCYP2C9 | |
| SCHEMBL28375872 | 0.84 | SLC16A3 (0.64) | LMNAALDH1A1MAPTCYP2C9CYP2C19 | |
| SCHEMBL29624737 | 0.84 | SLC16A3 (0.64) | LMNAALDH1A1MAPTCYP2C9CYP2C19 | |
| SCHEMBL30083674 | 0.83 | CA1 (0.56) | LMNAALDH1A1MAPTCYP2C9CYP2C19 | |
| SCHEMBL28369885 | 0.83 | CA1 (0.56) | LMNAALDH1A1MAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117049996-A | Synthesis method of 3-difluoromethylthio substituted indole compound | 都创(上海)医药科技股份有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-110938027-B | Synthetic method of indole derivatives | 河北凯诺中星科技有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-110938027-A | Synthetic method of indole derivatives | 天津大学 | 2020-03-31 | — | — | CN | disclosed |