Stearic Acid

Stearic Acid

SCHEMBL2837009

CCCCCCCCCCCCCCCCCC(=O)O.[Pd]

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.94
PPARG P37231 7/20 0.94
PPARD Q03181 7/20 0.94
PPARA Q07869 7/20 0.94
HDAC11 Q96DB2 5/20 0.94
TSHR P16473 4/20 0.94
PTPN1 P18031 3/20 0.94
ALDH1A1 P00352 2/20 0.94
TLR2 O60603 2/20 0.94
TDP1 Q9NUW8 2/20 0.94
FABP4 P15090 2/20 0.94
KMT2A Q03164 2/20 0.94
SLC22A6 Q4U2R8 1/20 0.94
SLC22A8 Q8TCC7 1/20 0.94
MEN1 O00255 1/20 0.94
ESR1 P03372 1/20 0.94
ALOX15 P16050 1/20 0.94
PDE4A P27815 1/20 0.94
PDE3A Q14432 1/20 0.94
HSD17B10 Q99714 1/20 0.94

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Myristic Acid SCHEMBL3768969 1.00 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
Octanoic Acid SCHEMBL3180463 1.00 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
Palmitic Acid SCHEMBL7063777 1.00 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
Dodecanoate SCHEMBL3180390 1.00 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
Heptanoate SCHEMBL11895282 1.00 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
Decanoic Acid SCHEMBL4267039 1.00 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
Behenic Acid SCHEMBL4352628 1.00 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
Pentadecanoic Acid SCHEMBL11895041 1.00 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL25295592 0.97 GPR84 (1.00) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL25287435 0.97 GPR84 (1.00) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10781397-B2 Lubricating oil compositions with engine wear protection EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-09-22 US claimed
US-20180298302-A1 LUBRICATING OIL COMPOSITIONS WITH ENGINE WEAR PROTECTION EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2018-10-18 US claimed
US-20180298301-A1 LUBRICATING OIL COMPOSITIONS WITH ENGINE WEAR PROTECTION EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2018-10-18 US claimed
US-10000721-B2 Lubricating oil compositions with engine wear protection EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2018-06-19 US claimed
EP-3240880-A1 LUBRICATING OIL COMPOSITIONS WITH ENGINE WEAR PROTECTION Exxonmobil Research And Engineering Company (US) 2017-11-08 EP claimed
EP-3240879-A1 LUBRICATING OIL COMPOSITIONS WITH ENGINE WEAR PROTECTION ExxonMobil Research and Engineering Company (US) 2017-11-08 EP claimed
WO-2016109376-A1 LUBRICATING OIL COMPOSITIONS WITH ENGINE WEAR PROTECTION EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2016-07-07 WO claimed
WO-2016109382-A1 LUBRICATING OIL COMPOSITIONS WITH ENGINE WEAR PROTECTION EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2016-07-07 WO claimed
US-20160186089-A1 LUBRICATING OIL COMPOSITIONS WITH ENGINE WEAR PROTECTION EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2016-06-30 US claimed
US-20160186084-A1 LUBRICATING OIL COMPOSITIONS WITH ENGINE WEAR PROTECTION EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2016-06-30 US claimed
CN-104043841-A Method for preparing metal nano material by utilizing hydrogen SUZHOU INNOVATIVE TECHNOLOGY MICROELECTRONIC MATERIAL CO LTD 2014-09-17 CN claimed
EP-0092601-A1 Compositions for undercoats OKUNO CHEMICAL INDUSTRY CO., LTD (JP) 1983-11-02 EP claimed
US-12605697-B1 Palladium/palladium oxide/calcium silicate/graphitic carbon nitride nanocomposite material IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) 2026-04-21 US disclosed
EP-4715023-A1 HEAT TRANSFER FLUID ExxonMobil Technology and Engineering Company (US) 2026-03-25 EP disclosed
EP-4715960-A1 METHOD FOR OPERATING A THERMAL MANAGEMENT ARRANGEMENT Dr. Ing. h.c. F. Porsche Aktiengesellschaft (DE) 2026-03-25 EP disclosed
US-20260081259-A1 METHOD FOR OPERATING A THERMAL MANAGEMENT ARRANGEMENT ExxonMobil Technology and Engineering Company (US) 2026-03-19 US disclosed
US-4176085-A SOLID PI-ALLYL COMPEXES COMPRISING A PALLADIUM SOURCE, A MONOTERTIARY PHOSPHINE, A REDUCING AGENT, A LEWIS ACID, AND A SILICA-BASED SUPPORT ATLANTIC RICHFIELD COMPANY (US) 1979-11-27 US disclosed
US-3983159-A Process for producing biphenylpolycarboxylic acid ester TEIJIN LIMITED (JA) 1976-09-28 US disclosed
US-3979466-A ALKALI CATALYST CONTINENTAL OIL COMPANY (US) 1976-09-07 US disclosed
US-3963787-A PALLADIUM CARBOXYLATE CATALYST TEIJIN LIMITED (JA) 1976-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605697-B1 Palladium/palladium oxide/calcium silicate/graphitic carbon nitride nanocomposite material PDCD4, PDCD1LG2, CD274 GPR84 3975/4885PPARG 2303/4885PPARD 3585/4885
US-20260081259-A1 METHOD FOR OPERATING A THERMAL MANAGEMENT ARRANGEMENT RAF1, PFKP, TP53RK GPR84 4462/4885PPARG 3679/4885PPARD 4422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.