Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1846642 | 0.79 | HSD11B1 (0.56) | CPB1ALDH1A1GAAHSD11B1TSHR | |
| SCHEMBL2825063 | 0.79 | HSD11B1 (0.56) | CPB1ALDH1A1GAAHSD11B1TSHR | |
| SCHEMBL12578487 | 0.79 | HSD11B1 (0.56) | CPB1ALDH1A1GAAHSD11B1TSHR | |
| SCHEMBL1845687 | 0.79 | HSD11B1 (0.56) | CPB1ALDH1A1GAAHSD11B1TSHR | |
| SCHEMBL1846641 | 0.79 | HSD11B1 (0.56) | CPB1ALDH1A1GAAHSD11B1TSHR | |
| SCHEMBL4708150 | 0.78 | IDH1 (0.50) | CPB1ALDH1A1GAAHSD11B1TSHR | |
| SCHEMBL1154459 | 0.78 | IDH1 (0.50) | CPB1ALDH1A1GAAHSD11B1TSHR | |
| SCHEMBL1154754 | 0.78 | IDH1 (0.50) | CPB1ALDH1A1GAAHSD11B1TSHR | |
| SCHEMBL1154453 | 0.78 | IDH1 (0.50) | CPB1ALDH1A1GAAHSD11B1TSHR | |
| SCHEMBL1154275 | 0.77 | CPB1 (0.50) | CPB1ALDH1A1GAAHSD11B1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507493-B2 | Amide and amidine derivatives and uses thereof | ABBVIE INC. (US) | 2013-08-13 | — | — | US | disclosed |
| US-20100267738-A1 | NOVEL AMIDE AND AMIDINE DERIVATIVES AND USES THEREOF | ABBOTT LABORATORIES (US) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267738-A1 | NOVEL AMIDE AND AMIDINE DERIVATIVES AND USES THEREOF | HSD11B2, HSD11B1, HSD17B2 | CPB1 1713/4885ALDH1A1 935/4885GAA 1238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.