SCHEMBL28370271

SCHEMBL28370271

O=C(O)CC(CCl)(CCl)CCl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
ALDH1A1 P00352 1/20 0.41
HMGCR P04035 1/20 0.41
CHRM1 P11229 1/20 0.41
TBXA2R P21731 1/20 0.41
ADRA1A P35348 1/20 0.41
CYP2C19 P33261 2/20 0.39
HIF1A Q16665 2/20 0.39
CYP2D6 P10635 1/20 0.39
CPT2 P23786 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
KDM4E B2RXH2 1/20 0.35
FFAR1 O14842 1/20 0.35
MIF P14174 1/20 0.34
ACLY P53396 3/20 0.33
LDHA P00338 1/20 0.32
SRR Q9GZT4 1/20 0.32
LMNA P02545 1/20 0.32
ALKBH5 Q6P6C2 1/20 0.32
SUCNR1 Q9BXA5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10567597 0.82 TBXA2R (0.39) TSHRALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL544773 0.79 ALDH1A1 (0.50) TSHRALDH1A1HMGCRCHRM1TBXA2R
Bicarbonate SCHEMBL28237125 0.76 TSHR (0.44) TSHRALDH1A1
SCHEMBL27887435 0.75 ALDH1A1 (0.36) TSHRALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL28878145 0.73
SCHEMBL1868224 0.73
SCHEMBL9770202 0.71 ALDH1A1 (0.43) TSHRALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL4807365 0.71 ALDH1A1 (0.43) TSHRALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL12386935 0.71 ALDH1A1 (0.43) TSHRALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL8529326 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110903183-A Novel preparation method of 3,3, 3-trifluoropropionic acid 湖南有色郴州氟化学有限公司 2020-03-24 CN disclosed