Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16096073 | 0.91 | LMNA (0.48) | LMNAMAPK1KDM4EMAPTHSD17B10 | |
| SCHEMBL28370239 | 0.83 | KDM4E (0.62) | LMNAMAPK1KDM4EMAPTHSD17B10 | |
| SCHEMBL19283497 | 0.81 | LMNA (0.47) | LMNAMAPK1KDM4EMAPTHSD17B10 | |
| SCHEMBL31083660 | 0.80 | KDM4E (0.51) | LMNAMAPK1KDM4EMAPTHSD17B10 | |
| SCHEMBL1805430 | 0.77 | LMNA (0.69) | LMNAMAPK1KDM4EMAPTHSD17B10 | |
| SCHEMBL10854514 | 0.77 | CA12 (0.47) | LMNAKDM4EMAPTHSD17B10ALDH1A1 | |
| SCHEMBL7491144 | 0.75 | MAOB (0.45) | LMNAMAPK1KDM4EMAPTHSD17B10 | |
| SCHEMBL2263402 | 0.75 | HDAC1 (0.43) | LMNAMAPK1KDM4EMAPTHSD17B10 | |
| SCHEMBL7825167 | 0.75 | ICAM1 (0.50) | LMNAMAPK1KDM4EMAPTHSD17B10 | |
| SCHEMBL26661110 | 0.74 | LMNA (0.52) | LMNAMAPK1KDM4EMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746424-A | MK2 inhibitors and uses thereof | 西建卡尔有限责任公司 | 2020-02-04 | — | — | CN | disclosed |