Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | GLA | P06280 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.53 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.53 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16096207 | 0.91 | KDM4E (0.66) | KDM4EALDH1A1GLAHPGDHSD17B10 | |
| SCHEMBL8148717 | 0.85 | KDM4E (0.58) | KDM4EALDH1A1GLAHPGDHSD17B10 | |
| SCHEMBL16096208 | 0.85 | IKBKB (0.45) | KDM4EALDH1A1GLAHPGDHSD17B10 | |
| SCHEMBL8141564 | 0.84 | KDM4E (0.68) | KDM4EALDH1A1GLAHPGDHSD17B10 | |
| SCHEMBL28370458 | 0.83 | LMNA (0.46) | KDM4EALDH1A1GLAHPGDHSD17B10 | |
| SCHEMBL17149279 | 0.82 | KDM4E (0.66) | KDM4EALDH1A1GLAHPGDHSD17B10 | |
| SCHEMBL31519888 | 0.81 | KDM4E (0.64) | KDM4EALDH1A1GLAHPGDHSD17B10 | |
| SCHEMBL2063500 | 0.81 | KDM4E (0.64) | KDM4EALDH1A1GLAHPGDHSD17B10 | |
| SCHEMBL4547547 | 0.81 | ALDH1A1 (0.64) | KDM4EALDH1A1GLAHPGDHSD17B10 | |
| SCHEMBL2063949 | 0.81 | KDM4E (0.64) | KDM4EALDH1A1GLAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746424-A | MK2 inhibitors and uses thereof | 西建卡尔有限责任公司 | 2020-02-04 | — | — | CN | disclosed |