Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14798802 | 0.84 | RAD51 (0.48) | ALDH1A1MAPTMEN1KMT2ATHRB | |
| SCHEMBL4273066 | 0.83 | CA2 (0.47) | ALDH1A1LMNA | |
| SCHEMBL28173004 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTMEN1KMT2ATHRB | |
| SCHEMBL28056138 | 0.78 | CA2 (0.54) | MAPT | |
| SCHEMBL27965195 | 0.76 | STAT5B (0.37) | MAPT | |
| SCHEMBL6815441 | 0.76 | ALDH1A1 (0.69) | ALDH1A1MAPTMEN1KMT2ATHRB | |
| SCHEMBL27994620 | 0.75 | ALDH1A1 (0.67) | ALDH1A1MAPTMEN1KMT2ATHRB | |
| SCHEMBL24140328 | 0.75 | NAMPT (0.61) | ALDH1A1MAPTMEN1KMT2ATHRB | |
| SCHEMBL14798779 | 0.74 | CA12 (0.72) | ALDH1A1MAPTMEN1KMT2ATHRB | |
| SCHEMBL8233776 | 0.73 | RAD51 (0.47) | ALDH1A1MAPTMEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108593-B | Substituted oxazole and thiazole-based carboxamide and urea derivatives as vanilloid receptor ligands II | 美迪福伦DBT有限公司 | 2020-03-24 | — | — | CN | disclosed |