Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | METAP2 | P50579 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | AXIN2 | Q9Y2T1 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 1/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28371229 | 0.93 | METAP2 (0.52) | TP53MAPTNPSR1MEN1KMT2A | |
| SCHEMBL28371334 | 0.93 | MAPT (0.54) | TP53MAPTNPSR1KMT2AUSP2 | |
| SCHEMBL28376533 | 0.93 | METAP2 (0.59) | TP53MAPTNPSR1MEN1KMT2A | |
| SCHEMBL28371820 | 0.91 | METAP2 (0.51) | TP53MAPTNPSR1USP2TSHR | |
| SCHEMBL28374960 | 0.91 | METAP2 (0.51) | TP53MAPTNPSR1MEN1KMT2A | |
| SCHEMBL28375380 | 0.91 | ALDH1A1 (0.55) | TP53MAPTNPSR1USP2TSHR | |
| SCHEMBL28886198 | 0.88 | ALDH1A1 (0.53) | TP53MAPTNPSR1MEN1KMT2A | |
| SCHEMBL28375277 | 0.86 | SMN1; SMN2 (0.62) | TP53MAPTNPSR1MEN1KMT2A | |
| SCHEMBL28371152 | 0.85 | NPSR1 (0.48) | TP53MAPTNPSR1MEN1KMT2A | |
| SCHEMBL28376596 | 0.84 | MEN1 (0.55) | TP53MAPTNPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104910082-B | 3,4, 5-trisubstituted-1, 2, 4-triazole thioether derivative and synthesis method and application thereof | 贵阳学院 | 2020-03-17 | — | — | CN | disclosed |