Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1384786 | 0.98 | SMN1; SMN2 (0.50) | SMN1; SMN2GAAALDH1A1NPSR1KMT2A | |
| Hydrochloric Acid SCHEMBL8411684 | 0.96 | SMN1; SMN2 (0.48) | SMN1; SMN2GAAALDH1A1NPSR1KMT2A | |
| SCHEMBL5707155 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2GAAALDH1A1KMT2ACYP3A4 | |
| SCHEMBL17165159 | 0.79 | ALDH1A1 (0.53) | SMN1; SMN2GAAALDH1A1KMT2AKDM4E | |
| SCHEMBL13383600 | 0.78 | LMNA (0.47) | NPSR1L3MBTL1KDM4EMAPT | |
| SCHEMBL11627004 | 0.77 | TP53 (0.53) | SMN1; SMN2GAAALDH1A1KMT2AMEN1 | |
| SCHEMBL4593908 | 0.76 | LMNA (0.46) | ALDH1A1NPSR1L3MBTL1KDM4EMAPT | |
| SCHEMBL5074242 | 0.75 | SMN1; SMN2 (0.56) | SMN1; SMN2GAAALDH1A1KMT2ACYP3A4 | |
| SCHEMBL7428953 | 0.75 | SMN1; SMN2 (0.56) | SMN1; SMN2GAAALDH1A1KMT2ACYP3A4 | |
| SCHEMBL6033251 | 0.74 | HPGD (0.41) | SMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110981854-B | Synthesis method of 2-amino-6- (1-alkyl piperidine-4-carbonyl) pyridine compound | 南京三元阳普医药科技有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-110981854-A | Synthesis method of 2-amino-6- (1-alkyl piperidine-4-carbonyl) pyridine compound | 南京三元阳普医药科技有限公司 | 2020-04-10 | — | — | CN | disclosed |