Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28373306 | 0.87 | CREBBP (0.41) | SRCEGFRNR4A2KMT2AKDM4E | |
| SCHEMBL28373429 | 0.87 | SRC (0.43) | SRCEGFRNR4A2KMT2AKDM4E | |
| SCHEMBL28369578 | 0.84 | ALDH1A1 (0.43) | SRCEGFRNR4A2KMT2AKDM4E | |
| SCHEMBL28369894 | 0.82 | NR4A2 (0.46) | NR4A2KMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL28435403 | 0.81 | SRC (0.43) | SRCEGFRNR4A2KMT2A | |
| SCHEMBL28373799 | 0.75 | KMT2A (0.41) | SRCEGFRNR4A2KMT2AKDM4E | |
| SCHEMBL28885915 | 0.75 | NR4A2 (0.50) | NR4A2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL28369964 | 0.72 | TSHR (0.44) | KMT2AKDM4EMEN1TSHRALDH1A1 | |
| SCHEMBL28369463 | 0.72 | ALDH1A1 (0.43) | SRCEGFRNR4A2KMT2AKDM4E | |
| SCHEMBL8252070 | 0.65 | CA1 (0.52) | KMT2AKDM4EMEN1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107149602-B | Application of indole compounds and derivatives thereof in preparation of anti-HIV drugs | 中国医学科学院药物研究所 | 2020-10-09 | — | — | CN | disclosed |
| CN-107176921-B | Indole compounds with antiviral activity in isatis root and derivatives thereof | 中国医学科学院药物研究所 | 2020-03-31 | — | — | CN | disclosed |