Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28373390 | 0.81 | SRC (0.44) | SRCEGFRKMT2ANR4A2 | |
| SCHEMBL28428982 | 0.76 | GPR84 (0.49) | LOXL2RAB9ASMN1; SMN2KMT2ANR4A2 | |
| SCHEMBL28369578 | 0.75 | ALDH1A1 (0.43) | SRCEGFRKMT2ANR4A2 | |
| SCHEMBL28375693 | 0.74 | KDM4E (0.45) | SRCEGFRCNR2 | |
| SCHEMBL28373306 | 0.73 | CREBBP (0.41) | SRCEGFRLOXL2RAB9AKMT2A | |
| SCHEMBL28369894 | 0.72 | NR4A2 (0.46) | SMN1; SMN2KMT2ANR4A2 | |
| SCHEMBL28373429 | 0.68 | SRC (0.43) | SRCEGFRKMT2ANR4A2 | |
| SCHEMBL23582664 | 0.68 | LOXL2 (0.59) | LOXL2NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL1002975 | 0.68 | HDAC6 (0.67) | CNR2 | |
| SCHEMBL5438238 | 0.67 | P2RX4 (0.66) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107149603-B | Application of indole compounds and derivatives thereof in preparation of anti-influenza virus drugs | 中国医学科学院药物研究所 | 2020-07-14 | — | — | CN | disclosed |