Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8581249 | 0.88 | GAA (0.58) | PTGS2NPC1RAB9ASMN1; SMN2GAA | |
| Bromide SCHEMBL28378533 | 0.86 | GAA (0.56) | PTGS2NPC1RAB9ASMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL11595275 | 0.86 | GAA (0.56) | PTGS2NPC1RAB9ASMN1; SMN2GAA | |
| Sulfuric Acid SCHEMBL28375810 | 0.85 | CA1 (0.50) | PTGS2NPC1RAB9ASMN1; SMN2GAA | |
| Phosphoric Acid SCHEMBL28375393 | 0.85 | PTGS2 (0.50) | PTGS2NPC1RAB9ASMN1; SMN2GAA | |
| Oxalic Acid SCHEMBL28200200 | 0.81 | PTGS2 (0.54) | PTGS2NPC1RAB9ASMN1; SMN2GAA | |
| Oxalic Acid SCHEMBL28374763 | 0.81 | PTGS2 (0.54) | PTGS2NPC1RAB9ASMN1; SMN2GAA | |
| Oxalic Acid SCHEMBL28373824 | 0.80 | RAB9A (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL2831390 | 0.77 | PTGS2 (0.67) | PTGS2NPC1RAB9ASMN1; SMN2GAA | |
| Oxalic Acid SCHEMBL20984197 | 0.77 | NPC1 (0.57) | PTGS2NPC1RAB9ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107663161-B | Continuous flow synthesis process of phenylhydrazine salt and substituted phenylhydrazine salt | 上海惠和化德生物科技有限公司 | 2020-04-10 | — | — | CN | claimed |
| CN-107663161-B | Continuous flow synthesis process of phenylhydrazine salt and substituted phenylhydrazine salt | 上海惠和化德生物科技有限公司 | 2020-04-10 | — | — | CN | disclosed |