Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 19/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 19/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28370736 | 0.93 | HCRTR1 (0.47) | HCRTR1HCRTR2SLC6A4 | |
| SCHEMBL28374107 | 0.90 | HCRTR1 (0.53) | HCRTR1HCRTR2 | |
| SCHEMBL28375766 | 0.88 | HCRTR1 (0.53) | HCRTR1HCRTR2 | |
| SCHEMBL28375771 | 0.88 | HTR6 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL28370934 | 0.84 | HCRTR1 (0.53) | HCRTR1HCRTR2SLC6A4 | |
| SCHEMBL28370216 | 0.83 | HCRTR2 (0.53) | HCRTR1HCRTR2SLC6A4 | |
| SCHEMBL28370936 | 0.81 | PTGS1 (0.52) | — | |
| SCHEMBL28370390 | 0.77 | HCRTR1 (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL15338611 | 0.76 | HCRTR1 (0.62) | HCRTR1HCRTR2 | |
| SCHEMBL28370626 | 0.76 | HTR6 (0.46) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106986859-B | Indole derivatives and uses thereof | 广东东阳光药业有限公司 | 2020-02-11 | — | — | CN | disclosed |