Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | HCRTR2 | O43614 | 14/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 13/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28370216 | 0.93 | HCRTR2 (0.53) | HTR6HCRTR2HCRTR1MTNR1AMTNR1B | |
| SCHEMBL28374107 | 0.88 | HCRTR1 (0.53) | HCRTR2HCRTR1HTR1A | |
| SCHEMBL28374151 | 0.88 | HCRTR1 (0.47) | HCRTR2HCRTR1 | |
| SCHEMBL28375766 | 0.87 | HCRTR1 (0.53) | HCRTR2HCRTR1 | |
| SCHEMBL28370934 | 0.83 | HCRTR1 (0.53) | HCRTR2HCRTR1HTR2A | |
| SCHEMBL28370736 | 0.83 | HCRTR1 (0.47) | HTR6HCRTR2HCRTR1MTNR1AMTNR1B | |
| SCHEMBL28370643 | 0.82 | MTNR1A (0.58) | HCRTR2MTNR1AMTNR1BHTR1AKMT2A | |
| SCHEMBL28374897 | 0.79 | HCRTR1 (0.49) | HTR6HCRTR2HCRTR1 | |
| SCHEMBL28374485 | 0.77 | HCRTR1 (0.49) | HTR6HCRTR2HCRTR1MTNR1A | |
| SCHEMBL15338611 | 0.75 | HCRTR1 (0.62) | HCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106986859-B | Indole derivatives and uses thereof | 广东东阳光药业有限公司 | 2020-02-11 | — | — | CN | disclosed |