Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL31376096 | 0.91 | MAPK1 (0.42) | MAPK1LMNAMC4RSIGMAR1BRD4 | |
| SCHEMBL28041798 | 0.90 | PDE4A (0.40) | MAPK1LMNAMC4RBRD4KMT2A | |
| Bicarbonate SCHEMBL28977799 | 0.85 | NOTUM (0.41) | LMNAMC4RSIGMAR1BRD4KMT2A | |
| SCHEMBL667066 | 0.84 | MC4R (0.46) | LMNAMC4RSIGMAR1MAPTFUCA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL28181600 | 0.84 | PDK1 (0.36) | MAPK1LMNAMC4RBRD4NPSR1 | |
| Bicarbonate SCHEMBL29180414 | 0.83 | NOTUM (0.41) | LMNAMC4RSIGMAR1BRD4KMT2A | |
| Acetic Acid SCHEMBL27851688 | 0.83 | LMNA (0.42) | LMNAMC4RBRD4KMT2ACYP2C9 | |
| Iodide SCHEMBL2195243 | 0.83 | MC4R (0.44) | LMNAMC4RSIGMAR1MAPTFUCA1 | |
| Hydrochloric Acid SCHEMBL383001 | 0.83 | MC4R (0.44) | LMNAMC4RSIGMAR1KDM4EMAPT | |
| Bromide SCHEMBL1179198 | 0.83 | MC4R (0.44) | LMNAMC4RSIGMAR1MAPTFUCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107532129-A | Efficient small volume nucleic acid synthesis | 生命技术公司 | 2018-01-02 | — | — | CN | disclosed |
| US-20100048327-A1 | Highly-Neutralized Golf Ball Compositions | ACUSHNET COMPANY | 2010-02-25 | — | — | US | disclosed |