Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | CCL2 | P13500 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16872444 | 0.88 | CNR2 (0.41) | BRD4CCL2HTR2AGAAL3MBTL1 | |
| SCHEMBL10688105 | 0.81 | BRD4 (0.46) | BRD4CCL2HTR2ADRD2SLC6A4 | |
| SCHEMBL10525335 | 0.80 | BRD4 (0.41) | BRD4CCL2HTR2ADRD2SLC6A4 | |
| SCHEMBL28323510 | 0.79 | PRCP (0.35) | BRD4CCL2HTR2ADRD2ADRA1A | |
| SCHEMBL24061842 | 0.78 | BRD4 (0.49) | BRD4CCL2HTR2ADRD2KDM4E | |
| SCHEMBL28310354 | 0.77 | ALDH1A1 (0.39) | BRD4CCL2HTR2AGAALMNA | |
| SCHEMBL28187418 | 0.71 | BRD4 (0.32) | BRD4CCL2RET | |
| SCHEMBL2453301 | 0.71 | BRD4 (0.40) | BRD4CCL2HTR2ADRD2L3MBTL1 | |
| SCHEMBL28570346 | 0.71 | BRD4 (0.40) | BRD4CCL2HTR2ADRD2GAA | |
| SCHEMBL28970511 | 0.69 | HTR2A (0.44) | BRD4CCL2HTR2ADRD2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110981799-B | Method for synthesizing quinolinone compound or isomers thereof | 天津理工大学 | 2021-02-19 | — | — | CN | claimed |
| CN-110981799-A | Method for synthesizing quinolinone compound or isomers thereof | 天津理工大学 | 2020-04-10 | — | — | CN | claimed |