Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.63 |
| ▸ | PDE4A | P27815 | 7/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28369857 | 0.81 | CCNT1 (0.56) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8166825 | 0.76 | SIRT2 (0.68) | SIRT2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27868039 | 0.72 | SIRT2 (0.66) | SIRT2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4754296 | 0.72 | SIRT2 (0.61) | SIRT2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28369506 | 0.72 | GSK3B (0.47) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27811062 | 0.71 | SIRT2 (0.64) | SIRT2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28375665 | 0.71 | GSK3B (0.44) | LMNAALDH1A1MAPTMEN1TSHR | |
| SCHEMBL8167903 | 0.70 | CCNE2 (0.72) | SIRT2 | |
| SCHEMBL28369252 | 0.70 | GSK3B (0.45) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28369715 | 0.70 | GSK3B (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110862396-B | Synthesis method of pyrrolo [3,4-c ] carbazole-1, 3(2H, 6H) -diketone compound | 浙江工业大学 | 2021-06-04 | — | — | CN | disclosed |
| CN-110862396-A | Synthesis method of pyrrolo [3,4-c ] carbazole-1, 3(2H,6H) -diketone compound | 浙江工业大学 | 2020-03-06 | — | — | CN | disclosed |