Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.61 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 3/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.55 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.55 |
| ▸ | HTR6 | P50406 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5355132 | 0.89 | F2RL3 (0.62) | SIRT2KCNH2DYRK1AF2RL3MEN1 | |
| SCHEMBL7441184 | 0.89 | F2RL3 (0.55) | SIRT2KCNH2DYRK1AF2RL3MEN1 | |
| SCHEMBL12260323 | 0.86 | F2RL3 (0.49) | SIRT2KCNH2DYRK1AF2RL3MEN1 | |
| SCHEMBL5357642 | 0.85 | F2RL3 (0.58) | SIRT2KCNH2DYRK1AF2RL3MEN1 | |
| SCHEMBL5309430 | 0.81 | PDE4A (0.58) | SIRT2MEN1ALDH1A1TSHRKMT2A | |
| Propionic Acid SCHEMBL19133584 | 0.79 | F2RL3 (0.64) | SIRT2KCNH2DYRK1AF2RL3MEN1 | |
| SCHEMBL7113697 | 0.79 | POLB (0.74) | MEN1ALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL5622616 | 0.78 | SMN1; SMN2 (0.60) | SIRT2MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL28938412 | 0.78 | F2RL3 (1.00) | SIRT2F2RL3ALDH1A1SMN1; SMN2PDE4A | |
| SCHEMBL7441180 | 0.78 | SIRT2 (0.53) | SIRT2F2RL3MEN1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147246-A1 | CATALYST FOR DEHYDROGENATION OF 4,5,6,7 TETRAHYDROINDOLE INTO INDOLE AND METHOD FOR PREPARING THEREOF | A.E. FAVORSKY IRKUTSK INSTITUTE OF CHEMISTRY SIBERIAN BRANCH RUSSIAN ACADEMY OF SCIENCES (IRIH SB RAS) (RU) | 2008-12-04 | — | — | WO | disclosed |