Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 4/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19091350 | 0.83 | APLNR (0.42) | APLNRCTSKCTSSCA1CA2 | |
| SCHEMBL6690055 | 0.83 | MEN1 (0.44) | APLNRCTSKCTSSCA1CA2 | |
| SCHEMBL2197146 | 0.83 | APLNR (0.42) | APLNRCTSKCTSSCA1CA2 | |
| SCHEMBL1222570 | 0.83 | MEN1 (0.44) | APLNRCTSKCTSSCA1CA2 | |
| SCHEMBL1222568 | 0.83 | MEN1 (0.44) | APLNRCTSKCTSSCA1CA2 | |
| SCHEMBL2194505 | 0.83 | APLNR (0.42) | APLNRCTSKCTSSCA1CA2 | |
| SCHEMBL2671597 | 0.77 | APLNR (0.46) | APLNRCTSKCTSSCA1CA2 | |
| SCHEMBL18756255 | 0.75 | APLNR (0.41) | APLNRCTSKCA1CA2CA7 | |
| SCHEMBL5325084 | 0.72 | APLNR (0.42) | APLNRCTSKCTSSCA1CA2 | |
| SCHEMBL8356011 | 0.72 | APLNR (0.42) | APLNRCTSKCTSSCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108084174-B | Preparation method of nifuratel | 北京金城泰尔制药有限公司 | 2020-04-17 | — | — | CN | claimed |
| CN-116947838-A | Production method of high-purity nifuratel | 北京金城泰尔制药有限公司沧州分公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-108084174-B | Preparation method of nifuratel | 北京金城泰尔制药有限公司 | 2020-04-17 | — | — | CN | disclosed |
| CN-108084174-B | Preparation method of nifuratel | 北京金城泰尔制药有限公司 | 2020-04-17 | — | — | CN | disclosed |