Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.40 |
| ▸ | F10 | P00742 | 4/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30541322 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HTTKDM4EPPARGPPARA | |
| SCHEMBL28369194 | 0.86 | FFAR1 (0.42) | ALDH1A1HTTKDM4ENLRP3F10 | |
| SCHEMBL21480517 | 0.86 | FFAR1 (0.42) | ALDH1A1HTTKDM4ENLRP3F10 | |
| SCHEMBL31303224 | 0.86 | FFAR1 (0.42) | ALDH1A1HTTKDM4ENLRP3F10 | |
| SCHEMBL30541308 | 0.86 | SLC1A3 (0.47) | ALDH1A1HTTKDM4EPPARGPPARA | |
| SCHEMBL28373603 | 0.86 | SLC1A3 (0.47) | ALDH1A1HTTKDM4EPPARGPPARA | |
| SCHEMBL30541466 | 0.84 | NLRP3 (0.37) | ALDH1A1HTTKDM4ENLRP3F10 | |
| SCHEMBL28368876 | 0.84 | NLRP3 (0.37) | ALDH1A1HTTKDM4ENLRP3F10 | |
| SCHEMBL28372807 | 0.83 | ALDH1A1 (0.41) | ALDH1A1HTTKDM4ENLRP3F10 | |
| SCHEMBL30671477 | 0.83 | ALDH1A1 (0.41) | ALDH1A1HTTKDM4ENLRP3F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110914242-A | Propionic acid derivatives and methods of use thereof | 阿维亚拉药品有限公司 | 2020-03-24 | — | — | CN | disclosed |