Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.41 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30541239 | 1.00 | TRPM8 (0.47) | TRPM8MAPTHSD17B1HSD17B2MMEL1 | |
| SCHEMBL30541357 | 0.88 | FFAR1 (0.48) | TRPM8MAPTALDH1A1HPGDRAB9A | |
| SCHEMBL28372580 | 0.88 | FFAR1 (0.48) | TRPM8MAPTALDH1A1HPGDRAB9A | |
| SCHEMBL30671470 | 0.86 | TRPM8 (0.47) | TRPM8MAPTHSD17B1HSD17B2ALDH1A1 | |
| SCHEMBL28372542 | 0.85 | ALDH1A1 (0.47) | MAPTHSD17B1HSD17B2CNR1ALDH1A1 | |
| SCHEMBL30541264 | 0.85 | ALDH1A1 (0.47) | MAPTHSD17B1HSD17B2CNR1ALDH1A1 | |
| SCHEMBL20546257 | 0.83 | FFAR1 (0.48) | HSD17B1HSD17B2MMEL1CNR1C3AR1 | |
| SCHEMBL20546255 | 0.83 | FFAR1 (0.48) | HSD17B1HSD17B2MMEL1CNR1C3AR1 | |
| SCHEMBL28368796 | 0.83 | POLB (0.41) | MAPTALDH1A1HPGDRAB9AKMT2A | |
| SCHEMBL30671476 | 0.83 | POLB (0.41) | MAPTALDH1A1HPGDRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110914242-B | Propionic acid derivatives and methods of use thereof | 阿维亚拉药品有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-110914242-A | Propionic acid derivatives and methods of use thereof | 阿维亚拉药品有限公司 | 2020-03-24 | — | — | CN | disclosed |