Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.46 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28127171 | 0.92 | KDM4E (0.52) | KDM4EALDH1A1HPGDGAAALOX15 | |
| SCHEMBL28379309 | 0.91 | F2RL3 (0.50) | KDM4EALDH1A1HPGDGAAGABRA2 | |
| SCHEMBL28379242 | 0.90 | CNR2 (0.56) | KDM4EALDH1A1HPGDGAAALOX15 | |
| SCHEMBL28376586 | 0.89 | GABRA2 (0.48) | KDM4EALDH1A1HPGDGAAALOX15 | |
| SCHEMBL28376283 | 0.88 | MDM2 (0.54) | KDM4EALDH1A1TSHRL3MBTL1GABRA2 | |
| SCHEMBL27899814 | 0.87 | PTGER1 (0.46) | KDM4EALDH1A1HPGDGAAL3MBTL1 | |
| SCHEMBL28127494 | 0.85 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDGAAALOX15 | |
| SCHEMBL2214355 | 0.82 | KDM4E (0.56) | KDM4EALDH1A1HPGDGAAALOX15 | |
| SCHEMBL2214644 | 0.82 | PTGER4 (0.56) | KDM4EALDH1A1HPGDGAAALOX15 | |
| SCHEMBL28127507 | 0.80 | CNR2 (0.55) | KDM4EALDH1A1GABRA2GABRB2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111012779-A | Application of harmine derivative in preparation of antibacterial drugs | 新疆华世丹药物研究有限责任公司 | 2020-04-17 | — | — | CN | disclosed |