Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.49 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.39 |
| ▸ | PDE4A | P27815 | 4/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18519470 | 0.89 | HPGD (0.51) | ALDH1A3ALDH3A1HPGDCSNK2A1ALDH1A1 | |
| SCHEMBL30511601 | 0.88 | HPGD (0.56) | ALDH1A3ALDH3A1HPGDCSNK2A1ALDH1A1 | |
| SCHEMBL25369211 | 0.88 | HPGD (0.56) | ALDH1A3ALDH3A1HPGDCSNK2A1ALDH1A1 | |
| SCHEMBL30694813 | 0.86 | HPGD (0.59) | ALDH1A3HPGDCSNK2A1ALDH1A1RORC | |
| SCHEMBL25369853 | 0.86 | HPGD (0.59) | ALDH1A3HPGDCSNK2A1ALDH1A1RORC | |
| SCHEMBL18519471 | 0.85 | KMO (0.46) | ALDH1A3ALDH3A1HPGDCSNK2A1ALDH1A1 | |
| SCHEMBL1299362 | 0.85 | HPGD (0.61) | ALDH1A3HPGDCSNK2A1ALDH1A1RORC | |
| SCHEMBL12263512 | 0.82 | HPGD (0.49) | HPGDCSNK2A1ALDH1A1RORCTTR | |
| SCHEMBL21190865 | 0.82 | SYK (0.42) | ALDH1A3ALDH3A1HPGDSYKALDH1A1 | |
| SCHEMBL28371304 | 0.82 | SYK (0.45) | ALDH1A3ALDH3A1HPGDSYKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110981876-B | 8-substituted styrylxanthine derivatives and uses thereof | 广东东阳光药业有限公司 | 2021-10-01 | — | — | CN | disclosed |
| CN-110981876-A | 8-substituted styrylxanthine derivatives and uses thereof | 广东东阳光药业有限公司 | 2020-04-10 | — | — | CN | disclosed |