Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.78 |
| ▸ | HPGD | P15428 | 5/20 | 0.78 |
| ▸ | HTT | P42858 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6544386 | 0.86 | ALDH1A1 (1.00) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL11366660 | 0.81 | ALDH1A1 (0.81) | ALDH1A1HPGDMEN1KMT2ANPSR1 | |
| SCHEMBL12717314 | 0.76 | SMN1; SMN2 (0.64) | ALDH1A1HPGDHTTMAPTNPC1 | |
| SCHEMBL7783342 | 0.76 | EPHX1 (0.73) | ALDH1A1HPGDHTTMAPTKMT2A | |
| SCHEMBL23004911 | 0.76 | HTT (0.56) | ALDH1A1HPGDHTTMAPTMEN1 | |
| SCHEMBL28226345 | 0.76 | HPGD (0.72) | ALDH1A1HPGDHTTMEN1KMT2A | |
| SCHEMBL3454940 | 0.74 | TDP1 (0.73) | ALDH1A1HPGDMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL21391252 | 0.74 | HPGD (0.83) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL15695713 | 0.74 | ALDH1A1 (0.67) | ALDH1A1HPGDHTTMAPTKMT2A | |
| SCHEMBL13332523 | 0.74 | EPHX2 (0.79) | ALDH1A1HPGDMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627672-B | Preparation method of dimemorfan phosphate and intermediate thereof | 广东东阳光药业有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-110627672-A | Preparation method of dimemorfan phosphate and intermediate thereof | 广东东阳光药业有限公司 | 2019-12-31 | — | — | CN | claimed |
| CN-110627672-B | Preparation method of dimemorfan phosphate and intermediate thereof | 广东东阳光药业有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-110627672-B | Preparation method of dimemorfan phosphate and intermediate thereof | 广东东阳光药业有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-110627672-A | Preparation method of dimemorfan phosphate and intermediate thereof | 广东东阳光药业有限公司 | 2019-12-31 | — | — | CN | disclosed |
| CN-110627672-A | Preparation method of dimemorfan phosphate and intermediate thereof | 广东东阳光药业有限公司 | 2019-12-31 | — | — | CN | disclosed |