Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 0.73 |
| ▸ | NPC1 | O15118 | 4/20 | 0.72 |
| ▸ | RAB9A | P51151 | 4/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28375511 | 0.86 | ALDH1A1 (0.78) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11366660 | 0.85 | ALDH1A1 (0.81) | ALDH1A1HPGDMEN1KMT2ACYP2C9 | |
| SCHEMBL23023152 | 0.78 | ALDH1A1 (0.63) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8691052 | 0.76 | MAPT (0.76) | ALDH1A1HPGDNPC1RAB9AGAA | |
| SCHEMBL3208992 | 0.76 | NPC1 (0.64) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL23495259 | 0.75 | ALDH1A1 (0.59) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13723908 | 0.75 | ALDH1A1 (0.72) | ALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL8201411 | 0.75 | ALDH1A1 (0.68) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10568721 | 0.75 | ALDH1A1 (0.72) | ALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL3456825 | 0.75 | RAB9A (1.00) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119143621-A | Method for preparing N- (2- (cyclohex-1-en-1-yl) ethyl) -2-p-methoxyphenyl acetamide | 江苏恩华药业股份有限公司 | 2024-12-17 | — | — | CN | claimed |
| CN-110483395-B | Purification method for salifying 1- (4-methoxybenzyl) -3,4,5,6,7, 8-hexahydroisoquinoline | 启东东岳药业有限公司 | 2021-03-23 | — | — | CN | claimed |
| EP-0834505-B1 | Process for the preparation of (Z)-1-[1-(4-Methoxybenzylidene)-1,2,3,4,5,6,7,8-octahydro-isoquinolin-2-yl]alkanones | HOFFMANN LA ROCHE (CH) | 2004-01-07 | — | — | EP | claimed |
| EP-0839135-B1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 1-(P-METHOXYBENZYL)-1,2,3,4,5,6,7,8-OCTAHYDROISOQUINOLINE | HOFFMANN LA ROCHE (CH) | 2001-10-10 | — | — | EP | claimed |
| US-5892044-A | ASYMMETRICALLY HYDROGENATING 1-(P-METHOXYBENZYL)-3,4,5,6,7,8-HEXAHYDROISOQUINOLINE OR SALT THEREOF IN PRESENCE OF CATALYTICALLY EFFECTIVE OPTICALLY ACTIVE IRIDIUM-PHOSPHINE COMPLEX | LONZA LTD. (CH) | 1999-04-06 | — | — | US | claimed |
| US-5849917-A | Process for the preparation of isoquinoline compounds | ROCHE VITAMINS INC. (US) | 1998-12-15 | — | — | US | claimed |
| EP-0839135-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 1-(P-METHOXYBENZYL)-1,2,3,4,5,6,7,8-OCTAHYDROISOQUINOLINE | LONZA AG (CH) | 1998-05-06 | — | — | EP | claimed |
| EP-0834505-A1 | Process for the preparation of (Z)-1-[1-(4-Methoxybenzylidene)-1,2,3,4,5,6,7,8-octahydro-isoquinolin-2-yl]alkanones | F. HOFFMANN-LA ROCHE AG (CH) | 1998-04-08 | — | — | EP | claimed |
| WO-1997003052-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 1-(P-METHOXYBENZYL)-1,2,3,4,5,6,7,8-OCTAHYDROISOQUINOLINE | LONZA AG (CH) | 1997-01-30 | — | — | WO | claimed |
| US-4496762-A | Process for the preparation of N-(2-(cyclo-hexen-1-yl)ethyl)-4-methoxybenzeneacetamide | EASTMAN KODAK COMPANY (US) | 1985-01-29 | — | — | US | claimed |
| JP-10114775-A | — | — | None | — | — | JP | disclosed |
| CN-119143621-B | Method for preparing N- (2- (cyclohex-1-en-1-yl) ethyl) -2-p-methoxyphenyl acetamide | 江苏恩华药业股份有限公司 | 2026-03-24 | — | — | CN | disclosed |
| CN-119143621-A | Method for preparing N- (2- (cyclohex-1-en-1-yl) ethyl) -2-p-methoxyphenyl acetamide | 江苏恩华药业股份有限公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-119143621-A | Method for preparing N- (2- (cyclohex-1-en-1-yl) ethyl) -2-p-methoxyphenyl acetamide | 江苏恩华药业股份有限公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-110483395-B | Purification method for salifying 1- (4-methoxybenzyl) -3,4,5,6,7, 8-hexahydroisoquinoline | 启东东岳药业有限公司 | 2021-03-23 | — | — | CN | disclosed |
| EP-0834505-A1 | Process for the preparation of (Z)-1-[1-(4-Methoxybenzylidene)-1,2,3,4,5,6,7,8-octahydro-isoquinolin-2-yl]alkanones | F. HOFFMANN-LA ROCHE AG (CH) | 1998-04-08 | — | — | EP | disclosed |
| EP-0834505-A1 | Process for the preparation of (Z)-1-[1-(4-Methoxybenzylidene)-1,2,3,4,5,6,7,8-octahydro-isoquinolin-2-yl]alkanones | F. HOFFMANN-LA ROCHE AG (CH) | 1998-04-08 | — | — | EP | disclosed |
| CN-1178218-A | Process for production of (Z)-1-[1-(4-methoxybenzylidene)-1,2,3,4,5,6,7,8-octahydro-isoquinolin-2-yl] alkanones of general formula | HOFFMANN LA ROCHE (CH) | 1998-04-08 | — | — | CN | disclosed |
| US-4496762-A | Process for the preparation of N-(2-(cyclo-hexen-1-yl)ethyl)-4-methoxybenzeneacetamide | EASTMAN KODAK COMPANY (US) | 1985-01-29 | — | — | US | disclosed |
| US-4496762-A | Process for the preparation of N-(2-(cyclo-hexen-1-yl)ethyl)-4-methoxybenzeneacetamide | EASTMAN KODAK COMPANY (US) | 1985-01-29 | — | — | US | disclosed |