SCHEMBL2837557

SCHEMBL2837557

Nc1c(OCCO)cc(O)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.46
KMT2A Q03164 5/20 0.46
MAPT P10636 4/20 0.46
TDP1 Q9NUW8 3/20 0.46
MAPK1 P28482 3/20 0.46
HPGD P15428 2/20 0.46
MAOA P21397 2/20 0.46
ALDH1A1 P00352 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
KDM4E B2RXH2 2/20 0.46
DAPK1 P53355 2/20 0.46
TTR P02766 2/20 0.46
CYP1A1 P04798 2/20 0.46
BRCA1 P38398 2/20 0.46
CYP3A4 P08684 1/20 0.46
HSPD1 P10809 1/20 0.46
ALOX15 P16050 1/20 0.46
ALOX12 P18054 1/20 0.46
ACHE P22303 1/20 0.46
MAOB P27338 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29710714 1.00 MEN1 (0.46) MEN1KMT2AMAPTTDP1MAPK1
SCHEMBL5691087 0.94 KCNA3 (0.43) MEN1KMT2AMAPTTDP1MAPK1
SCHEMBL20126396 0.93 PTPN1 (0.46) MEN1KMT2AMAPTTDP1MAPK1
SCHEMBL10085670 0.92 MEN1 (0.49) MEN1KMT2AMAPTTDP1MAPK1
SCHEMBL2833211 0.91 MEN1 (0.43) MEN1KMT2AMAPTTDP1MAPK1
SCHEMBL11753630 0.91 MEN1 (0.43) MEN1KMT2AMAPTTDP1MAPK1
SCHEMBL29710715 0.91 MEN1 (0.43) MEN1KMT2AMAPTTDP1MAPK1
SCHEMBL10086156 0.88 KCNA3 (0.47) MEN1KMT2AMAPTTDP1MAPK1
SCHEMBL11801539 0.88 MEN1 (0.45) MEN1KMT2AMAPTTDP1MAPK1
SCHEMBL9358121 0.87 ADORA2A (0.46) MEN1KMT2AMAPTTDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2039728-B1 Red paint mixture LANXESS DEUTSCHLAND GMBH (DE) 2012-05-02 EP disclosed
US-20100110242-A1 Anthraquinone dye containing material, composition including the same, camera including the same, and associated methods CHEIL INDUSTRIES, INC. (KR) 2010-05-06 US disclosed
EP-2039728-A2 Red paint mixture Lanxess Deutschland GmbH (DE) 2009-03-25 EP disclosed
US-7105688-B2 Ethylenically-unsaturated red anthraquinone dyes EASTMAN CHEMICAL COMPANY (US) 2006-09-12 US disclosed
EP-1658338-A1 ETHYLENICALLY-UNSATURATED RED ANTHRAQUINONE DYES EASTMAN CHEMICAL COMPANY (US) 2006-05-24 EP disclosed
WO-2005021662-A1 ETHYLENICALLY-UNSATURATED RED ANTHRAQUINONE DYES EASTMAN CHEMICAL COMPANY (US) 2005-03-10 WO disclosed
US-20050049425-A1 Ethylenically-unsaturated red anthraquinone dyes EASTMAN CHEMICAL COMPANY 2005-03-03 US disclosed
EP-0261075-B1 PROCESS FOR THE PREPARATION OF DISPERSIVE DYES CIBA-GEIGY AG (CH) 1992-03-11 EP disclosed
US-4804767-A Process for the preparation of disperse dyes CIBA-GEIGY CORPORATION (US) 1989-02-14 US disclosed
EP-0261075-A2 Process for the preparation of dispersive dyes CIBA-GEIGY AG (CH) 1988-03-23 EP disclosed
EP-0071576-B1 PROCESS FOR THE PREPARATION OF 1-AMINO-4-HYDROXY ANTHRAQUINONES CIBA-GEIGY AG (CH) 1985-01-23 EP disclosed
US-4485043-A Process for producing 1-amino-4-hydroxy-anthraquinones CIBA-GEIGY AG (CH) 1984-11-27 US disclosed
US-4436906-A Anthraquinone dyes for cellulose-containing fibers and process for producing the same MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1984-03-13 US disclosed
EP-0071576-A1 Process for the preparation of 1-amino-4-hydroxy anthraquinones CIBA-GEIGY AG (CH) 1983-02-09 EP disclosed
US-4360357-A Transfer-printing carriers: red component dye mixture for polyacrylonitrile CIBA-GEIGY AG (CH) 1982-11-23 US disclosed
EP-0061428-A2 Porous support for transfer printing, its manufacture and use CIBA-GEIGY AG (CH) 1982-09-29 EP disclosed
US-4202838-A Sulphonated condensation products CIBA-GEIGY CORPORATION (US) 1980-05-13 US disclosed
US-4081240-A Process for dyeing fully synthetic textile material CIBA-GEIGY AG (CH) 1978-03-28 US disclosed
US-3971740-A DYES FOR POLYESTER FIBERS CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3968131-A POLYOXYETHYLENE GLYCOL BASF AKTIENGESELLSCHAFT (DT) 1976-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100110242-A1 Anthraquinone dye containing material, composition including the same, camera including the same, and associated methods ACR, PAM, AAAS MEN1 344/4885KMT2A 1033/4885MAPT 1501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.