Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30266517 | 1.00 | LMNA (0.61) | LMNAMAPK1HCAR2NPC1L3MBTL1 | |
| SCHEMBL2719532 | 0.89 | TRPM8 (0.71) | LMNAMAPK1HCAR2ALDH1A1THRB | |
| SCHEMBL2719528 | 0.89 | TRPM8 (0.71) | LMNAMAPK1HCAR2ALDH1A1THRB | |
| SCHEMBL28376870 | 0.85 | MAPT (0.59) | LMNAMAPK1HCAR2ALDH1A1THRB | |
| SCHEMBL3164680 | 0.81 | HCAR2 (0.62) | LMNAHCAR2NPC1ALDH1A1MAPT | |
| SCHEMBL6937661 | 0.81 | SMN1; SMN2 (0.58) | LMNAHCAR2ALDH1A1MAPTHTT | |
| SCHEMBL6937665 | 0.81 | SMN1; SMN2 (0.58) | LMNAHCAR2ALDH1A1MAPTHTT | |
| SCHEMBL18983992 | 0.79 | HCAR2 (0.59) | LMNAMAPK1HCAR2NPC1ALDH1A1 | |
| SCHEMBL9520111 | 0.78 | HCAR2 (0.62) | LMNAHCAR2NPC1ALDH1A1MAPT | |
| SCHEMBL9520106 | 0.78 | HCAR2 (0.62) | LMNAHCAR2NPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111072597-B | Piperine derivative and preparation method and application thereof | 四川大学 | 2022-12-09 | — | — | CN | disclosed |
| CN-111018735-B | Preparation method of cinnamamide compound | 河南农业大学 | 2021-09-07 | — | — | CN | disclosed |
| CN-111072597-A | Piperine derivative and preparation method and application thereof | 四川大学 | 2020-04-28 | — | — | CN | disclosed |
| CN-111018735-A | Preparation method of cinnamamide | 河南农业大学 | 2020-04-17 | — | — | CN | disclosed |