Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.43 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11217696 | 0.92 | HSD17B3 (0.55) | TRPM8NPC1L3MBTL1HSD17B3PTGS2 | |
| SCHEMBL10716741 | 0.84 | TYR (0.61) | KMT2APTGS2APPMAPTRAB9A | |
| SCHEMBL10716746 | 0.84 | TYR (0.61) | KMT2APTGS2APPMAPTRAB9A | |
| SCHEMBL1016905 | 0.82 | MAPT (0.57) | L3MBTL1HSD17B3KMT2AALDH1A1LMNA | |
| SCHEMBL16431497 | 0.82 | MAPT (0.57) | L3MBTL1HSD17B3KMT2AALDH1A1LMNA | |
| SCHEMBL4900457 | 0.82 | HSD11B1 (0.62) | HSD17B3KMT2AAPPALDH1A1LMNA | |
| SCHEMBL9720425 | 0.82 | MEN1 (0.49) | TRPM8NPC1L3MBTL1HSD17B3KMT2A | |
| SCHEMBL2218286 | 0.82 | MEN1 (0.49) | TRPM8NPC1L3MBTL1HSD17B3KMT2A | |
| SCHEMBL3413340 | 0.82 | CYP1A2 (0.62) | NPC1KMT2AALDH1A1LMNAMAPT | |
| N,N-Dimethylcinnamamide SCHEMBL3743395 | 0.82 | NPC1 (0.65) | TRPM8NPC1L3MBTL1KMT2APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111018735-B | Preparation method of cinnamamide compound | 河南农业大学 | 2021-09-07 | — | — | CN | disclosed |
| CN-111018735-A | Preparation method of cinnamamide | 河南农业大学 | 2020-04-17 | — | — | CN | disclosed |