Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28344028 | 0.88 | S1PR2 (0.57) | S1PR2MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL28369737 | 0.86 | PTPN5 (0.51) | S1PR2TSHRLMNAGAAHTT | |
| SCHEMBL28369732 | 0.85 | S1PR2 (0.49) | S1PR2MEN1KMT2ATSHRLMNA | |
| SCHEMBL28373077 | 0.85 | S1PR2 (0.57) | S1PR2MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL28374362 | 0.85 | TSHR (0.54) | S1PR2MEN1KMT2ATSHRHTT | |
| SCHEMBL28369520 | 0.85 | S1PR2 (0.49) | S1PR2MEN1KMT2ATSHRLMNA | |
| SCHEMBL28167902 | 0.84 | KDM4E (0.57) | S1PR2MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL28369331 | 0.84 | ALDH1A1 (0.59) | S1PR2MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL28375698 | 0.84 | PTPN5 (0.56) | S1PR2MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL28369298 | 0.83 | KMT2A (0.60) | S1PR2MEN1KMT2ATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107149602-B | Application of indole compounds and derivatives thereof in preparation of anti-HIV drugs | 中国医学科学院药物研究所 | 2020-10-09 | — | — | CN | disclosed |
| CN-107149603-B | Application of indole compounds and derivatives thereof in preparation of anti-influenza virus drugs | 中国医学科学院药物研究所 | 2020-07-14 | — | — | CN | disclosed |
| CN-107176921-B | Indole compounds with antiviral activity in isatis root and derivatives thereof | 中国医学科学院药物研究所 | 2020-03-31 | — | — | CN | disclosed |