SCHEMBL28375718 — predicted protein targets

Predicted protein targets (top 19)

	gene	UniProt	supporting neighbours	confidence
▸	TERT	O14746	2/20	0.57

▸	FLT3	P36888	3/20	0.43

▸	TUBB4A	P04350	2/20	0.40

▸	TUBB	P07437	2/20	0.40

▸	TUBA3C	P0DPH7	2/20	0.40

▸	TUBA1B	P68363	2/20	0.40

▸	TUBA4A	P68366	2/20	0.40

▸	TUBB4B	P68371	2/20	0.40

▸	TUBB3	Q13509	2/20	0.40

▸	TUBB2A	Q13885	2/20	0.40

▸	TUBB8	Q3ZCM7	2/20	0.40

▸	TUBA3E	Q6PEY2	2/20	0.40

▸	TUBA1A	Q71U36	2/20	0.40

▸	TUBA1C	Q9BQE3	2/20	0.40

▸	TUBB6	Q9BUF5	2/20	0.40

▸	TUBB2B	Q9BVA1	2/20	0.40

▸	TUBB1	Q9H4B7	2/20	0.40

▸	TUBB8B	A6NNZ2	1/20	0.39

▸	EGFR	P00533	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL28375719	1.00	TERT (0.57)	TERTFLT3TUBB4ATUBBTUBA3C
SCHEMBL28374042	0.90	TERT (0.54)	TERTTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL28374039	0.90	TERT (0.54)	TERTTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL28373459	0.88	TERT (0.51)	TERTEGFR
SCHEMBL28373456	0.88	TERT (0.51)	TERTEGFR
SCHEMBL28377952	0.85	TERT (0.54)	TERTFLT3
SCHEMBL28377954	0.85	TERT (0.54)	TERTFLT3
SCHEMBL28378147	0.84	TERT (0.59)	TERTFLT3
SCHEMBL28378150	0.84	TERT (0.59)	TERTFLT3
SCHEMBL28373320	0.81	PTGS2 (0.42)	TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-108503648-B	Styryl pyrazolopyrimidine compound, pharmaceutical composition, preparation method and application	安徽医科大学	2020-04-14	—	—	CN	disclosed