Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CCL2 | P13500 | 1/20 | 0.38 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2453301 | 0.94 | BRD4 (0.40) | CNR2CNR1BRD4CCL2ALDH1A1 | |
| SCHEMBL10525335 | 0.88 | BRD4 (0.41) | BRD4CCL2ALDH1A1CYP2D6GAA | |
| SCHEMBL16872444 | 0.82 | CNR2 (0.41) | CNR2CNR1BRD4CCL2SETD7 | |
| SCHEMBL11036624 | 0.77 | ATM (0.46) | CNR2CNR1BRD4CCL2SETD7 | |
| SCHEMBL15923751 | 0.76 | CNR2 (0.36) | CNR2CNR1BRD4CCL2SETD7 | |
| SCHEMBL28570346 | 0.76 | BRD4 (0.40) | CNR2CNR1BRD4CCL2ALDH1A1 | |
| SCHEMBL28378808 | 0.73 | BRD4 (0.49) | BRD4CCL2ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL10688105 | 0.70 | BRD4 (0.46) | BRD4CCL2ALDH1A1CYP2D6GAA | |
| SCHEMBL28374476 | 0.69 | BRD4 (0.41) | BRD4CCL2ALDH1A1CYP2D6GAA | |
| SCHEMBL5290380 | 0.65 | ALDH1A1 (0.42) | CNR2CNR1ALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110981799-B | Method for synthesizing quinolinone compound or isomers thereof | 天津理工大学 | 2021-02-19 | — | — | CN | claimed |
| CN-110981799-A | Method for synthesizing quinolinone compound or isomers thereof | 天津理工大学 | 2020-04-10 | — | — | CN | claimed |